Brain Imaging in Early Alzheimer's Disease (AD)


The goal of this project was to develop imaging biomarkers that can identify people at risk for developing AD, help with early diagnosis, prognosis or therapeutic decision-making. The project was to continued to implement and develop sophisticated imaging methodologies and test their potential for becoming primary and secondary outcome measures for clinical trials in AD and MCI. Another important goal of this project was to identify the structural brain changes associated with conversion from MCI to AD and from normal cognition to MCI and investigate the associations between cognitive, behavioral and laboratory measures and structural biomarkers in the AD spectrum. This project utilized data from ADNI and our local imaging database. This research project period has ended. If you have any questions, please send an email to This email address is being protected from spambots. You need JavaScript enabled to view it..

Sponsors: NIH/NIA K23 AG 026803/ADRC – PROJECT 1
Principal Investigator: Liana Apostolova, MD, MSCR
Co-Investigator: Paul Thompson, PhD