Restrepo, Lucas, M.D., Ph.D.
  • Health Sciences Assistant Professor of Neurology, David Geffen School of Medicine at UCLA

  • Comprehensive Stroke and Vascular Neurology Program

Restrepo, Lucas, M.D., Ph.D.


Comprehensive Stroke and Vascular Neurology Program
Department of Neurology at UCLA
710 Westwood Plaza
Los Angeles, CA 90095
Tel: (310) 794-6379
Clinic Appts: (310) 794-1195
Clinic Fax: (310) 794-7491
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.





Stroke and Vascular Neurology, Alzheimer's Disease, Dementia, and Memory Disorders.



Lucas Restrepo obtained his MD degree from the Health Science Institute in Colombia, South America in 1993, completing his neurology residency at Georgetown University in 2000 and a stroke fellowship at Johns Hopkins Hospital with Robert J. Wityk in 2002. He has earned several academic awards, including "intern of the year" at the University of Texas Health Science Center in San Antonio in 1996 and being named "neurology attending of the year" by the UCLA neurology residents in 2006 and 2010. He earned a PhD in Molecular and Cell Biology at Arizona State University in 2011 under the mentoring of Stephen Albert Johnston. Dr. Restrepo has published over 40 peer-reviewed papers, some with relevant impact. Two of his papers about advanced MRI techniques and transcranial Doppler ultrasound for the evaluation of the pathophysiology of brain ischemia were selected as "best paper (s) published in the Journal of Neuroimaging" for 2 consecutive years (2003 and 2004). Dr. Restrepo is co-inventor of several cooling devices for neuroprotection and helped develop a blood test for Alzheimer’s Disease. He is currently a Clinical Assistant Professor of Neurology at the David Geffen School of Medicine at UCLA.



  • M.D., Medicine and Surgery, Health Sciences Institute (CES), Medellin, Colombia, 1986-1993.
  • Internship, Internal Medicine, U Texas Health Science Center, San Antonio, Texas, 1996-1997.
  • Residency, Neurology, Georgetown University, Washington, DC, 1997-2000.
  • Fellowship I, Yale University, New Haven, Connecticut, 2000-2001.
  • Fellowship II, Johns Hopkins Hospital, Baltimore, Maryland, 2001-2003.
  • M.S., Molecular and Cellular Biology, Arizona State University (ASU), Tempe, Arizona, 2006-2010.
  • Ph.D., Molecular and Cellular Biology, Arizona State University (ASU), Tempe, Arizona, 2006-2011.


Honors and Awards

  • Golden Hammer Award” (Neurology Attending of the Year) Presented by Neurology Residents, University of California, Los Angeles, June 2010.
  • ”Stroke in Emergency Medicine Award,” American Heart Association/International Stroke Conference, February 2010, San Antonio, Texas.
  • ”Neurology Attending of the Year” Presented by Neurology Residents, University of California, Los Angeles, June 2007.
  • “John and Sophia Prockop Memorial Lectureship” for a manuscript that was judged to have “outstanding value to the development and success of the Journal of Neuroimaging”, Spring 2006. [J Neuroimaging 2005;15:254-260]
  • ”John and Sophia Prockop Memorial Lectureship” award for “the highest quality manuscript published in the prior year in the Journal of Neuroimaging”, Spring 2004. [J Neuroimaging 2003; 13:34-42]
  • ”Outstanding Service”, 2 recognitions, Veterans Affairs, Washington, D.C., Spring 1998.
  • ”Intern of the Year”, University of Texas SCSA, Spring 1997.
  • “Top 10 Best Posters”, American College of Physicians meeting (1997), San Antonio, Texas.


Board Certifications

2005 Neurology, American Board of Psychiatry and Neurology


Publications (selected peer-reviewed publications)

  • Restrepo L, Stafford P, Johnston SA. Feasibility of an early Alzheimer's disease immunosignature diagnostic test. J Neuroimmunol 2013;254:154-160. PMID: 23084373
  • Moscato M, Boon-Unge K, Restrepo L. Enhancing brain lesions in a renal transplant patient. The Neurohospitalist. 2013;1:15-19. doi:10.1177/1941874412459333. PMID: 23983883; PMCID: PMC3726124
  • Alderazi YJ, Chang J, Yang YP, Teleb M, Chapple K, Awad A, Restrepo L. Impact of Protocol Deviations in Acute Ischemic Stroke Treated With Intravenous rt-PA Within 4.5 Hours After Symptom Onset. The Neurohospitalist 2012;2:82-86. doi:10.1177/1941874412441802. PMID: 23983868; PMCID: PMC3726086
  • Restrepo L, Stafford P, Magee DM, Johnston SA. Application of immunosignatures to the assessment of Alzheimer's disease. Annals of Neurology 2011; 70: 286-295. PMID:21823156
  • Chang J, Teleb M, Alderazi Y, Yang J, Frey J, Restrepo L. Stroke mimics treated with i.v. fibrinolysis. J Stroke Cerebrovasc Dis. 2011 Jun 1. [Epub ahead of print] PMID:21640609
  • Likosky D, Shulman S, Restrepo L, Freeman WD. Survey of neurohospitalists: subspecialty definition and practice characteristics. Front Neurol. 2010 Jun 14;1:9. PMID:21206522; PMCID: PMC3009448
  • Restrepo L. Arizona Immigration Law and clinical practice. N Engl J Med. 2010 Jun 24;362(25):2432. PMID:20519676
  • Sanossian N, Starkman S, Liebeskind DS, Ali LK, Restrepo L, Hamilton S, Conwit R, Saver JL; FAST-MAG Trial Investigators. Simultaneous ring voice-over-Internet phone system enables rapid physician elicitation of explicit informed consent in prehospital stroke treatment trials. Cerebrovasc Dis. 2009;28(6):539-44. PMID:19844092; PMCID: PMC2914352
  • Bang OY, Ovbiagele B, Liebeskind DS, Restrepo L, Yoon SR, Saver JL. Clinical determinants of infarct pattern subtypes in large vessel atherosclerotic stroke. J Neurol. 2009;256(4):591-599. PMID:19444533; PMCID: PMC2745818
  • Restrepo L, Bang OY, Ovbiagele B, Liebeskind DS, Starkman S, Buck B, Vinuela F, Duckwiler G, Jahan R, Saver JL. Impact of History of Hyperlipidemia and Statin Therapy on Acute Ischemic Stroke Outcomes after Intra-Arterial Fibrinolysis and Percutaneous Mechanical Embolectomy. Cerebrovasc Dis 2009;28:384-390. PMID:19713698; PMCID: PMC2909704


Health Professionals