Shino Magaki, M.D., Ph.D.
Assistant Professor of Neuropathology
About
David Geffen School of Medicine at UCLA
UCLA Path & Lab Med
BOX 951732, CHS 1P-250
Los Angeles, CA 90095-1732
Phone:(310) 794-0568
Email: smagaki@mednet.ucla.edu
Biography
Dr. Shino Magaki obtained her MD and PhD at Loma Linda University School of Medicine (LLUSM) and did her anatomic and clinical pathology residency followed by a neuropathology fellowship at UCLA David Geffen School of Medicine. She was an assistant professor in the Department of Pathology and Human Anatomy at LLUSM for 2 years before joining the faculty at the Department of Pathology and Laboratory Medicine at UCLA.
Specialty
Neuropathology
Affiliations
Education and Degrees
B.S., Biochemistry, summa cum laude, University of Nevada-Las Vegas (UNLV)
Ph.D., Biochemistry, Dean’s Award, Loma Linda University (LLU) School of Medicine
M.D., President’s Award, LLU School of Medicine
Resident, Anatomic and Clinical Pathology, David Geffen School of Medicine at University of California-Los Angeles (UCLA)
Chief Resident, Anatomic and Clinical Pathology, David Geffen School of Medicine at UCLA
Neuropathology Fellow, David Geffen School of Medicine at UCLA
Awards and Honors
2005 -- Selma Andrews Travel Award, LLU
2008 -- McGraw-Hill Companies Medical Publishing Lange Student Award
2008 -- Walter E. Macpherson Summer Research Scholarship, LLU
2010 -- Walter E. Macpherson Student-Faculty Research Award, LLU
2011 -- American Association of Anatomists Travel Award
2011 -- American Academy of Neurology Medical Student Prize for Excellence
Board Certifications
American Board of Pathology, Anatomic and Clinical Pathology
American Board of Pathology, Neuropathology
Publications
(selected peer-reviewed publications)
Chin V, Valinluck V, Magaki S, Ryu J. KpnBI is the prototype of a new family (IE) of bacterial type I restriction-modification system. Nucleic Acids Res 2004;32:e138.
Uudus N, Magaki S, Balakrishnan N. Quantum mechanical investigation of rovibrational relaxation of H2 and D2 by collisions with Ar atoms. J Chem Phys 2005;122:024304.
Magaki S, Mueller C, Dickson C, Kirsch W. Increased production of inflammatory cytokines in mild cognitive impairment. Exp Gerontol 2007;42:233-240.
Magaki S, Mueller C, Yellon SM, Fox J, Kim J, Snissarenko E, Chin V, Ghosh MC, Kirsch WM. Regional dissection and determination of loosely bound and non-heme iron in the developing mouse brain. Brain Res 2007;1158:144-150.
Magaki S, Raghavan R, Mueller C, Oberg KC, Vinters HV, Kirsch WM. Iron, copper, and iron regulatory protein 2 in Alzheimer's disease and related dementias. Neurosci Lett 2007;418:72-76.
Magaki S, Yellon SM, Mueller C, Kirsch WM. Immunophenotypes in the circulation of patients with mild cognitive impairment. J Psychiatr Res 2008;42:240-246.
Mueller C, Magaki S, Schrag M, Ghosh MC, Kirsch WM. Iron regulatory protein 2 is involved in brain copper homeostasis. J Alzheimers Dis 2009;18:201-210.
Mueller C, Zhou W, Vanmeter A, Heiby M, Magaki S, Ross MM, Espina V, Schrag M, Dickson C, Liotta LA, Kirsch WM. The heme degradation pathway is a promising serum biomarker source for the early detection of Alzheimer's disease. J Alzheimers Dis 2010;19:1081-1091.
Mueller C, Schrag M, Crofton A, Stolte J, Muckenthaler MU, Magaki S, Kirsch W. Altered serum iron and copper homeostasis predicts cognitive decline in mild cognitive impairment. J Alzheimers Dis 2012;29:341-350.
Magaki S, Yong WH, Khanlou N, Tung S, Vinters HV. Comorbidity in dementia: update of an ongoing autopsy study. J Am Geriatr Soc 2014;62:1722-1728.
Magaki S, Gardner T, Khanlou N, Yong WH, Salamon N, Vinters HV. Brain biopsy in neurologic decline of unknown etiology. Hum Pathol 2015;46:499-506.
Magaki SD, Bhuta S, Abemayor E, Nabili V, Sepahdari AR, Lai CK. Carcinoma ex-pleomorphic adenoma of the parotid gland consisting of high-grade salivary duct carcinoma and keratinizing squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol 2015;120:e169-173.
Magaki S, Chang E, Hammond RR, Yang I, Mackenzie IRA, Chou BT, Choi SI, Jen JC, Pope WB, Bell DA, Vinters HV. Two cases of rheumatoid meningitis. Neuropathology 2016;36:93-102.
Arcega R, Wu JX, Magaki S, Donahue TR, Wang H. A Hitherto Undescribed Benign Mesenchymal Polyp of the Gallbladder- Edematous Angiomyolipoma-like Polyp. Acta Gastroenterol Belg 2016;79:245-250.
Stiles AR. Simon MT. Stover A. Eftekharian S, Khanlou N, Wang HL, Magaki S, Lee H, Partynski K, Dorrani N, Chang R, Martinez-Agosto JA, Abdenur JE. Mutations in TFAM, encoding mitochondrial transcription factor A, cause neonatal liver failure associated with mtDNA depletion. Mol Genet Metab 2016;119:91-99.
Magaki S, Ostrzega N, Ho E, Yim C, Wu P, Vinters HV. Hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus in the central nervous system. Human Pathol 2017;59:108-112.
Malhotra K, Magaki SD, Cobos Sillero MI, Vinters HV, Jahan R, Brown RD Jr, Liebeskind DS. Atypical case of perimesencephalic subarachnoid hemorrhage. Neuropathology 2016;37:272-274.
Magaki S, Ng DW, Terashima KH, Keener AM, Salamon N, Karnezis S, Macyszyn L, Vinters HV. Amyloid-β related angiitis: a report of two cases with unusual presentations. Human Pathol 2017;64:191-197.
Movassaghi M, Shabihkhani M, Hojat SA, Williams RR, Chung LK, Im K, Lucey GM, Wei B, Mareninov S, Wang MW, Ng DW, Tashjian RS, Magaki S, Perez-Rosendahl M, Yang I, Khanlou N, Vinters HV, Liau LM, Nghiemphu PL, Lai A, Cloughesy TF, Yong WH. Early experience with formalin-fixed paraffin-embedded (FFPE) based commercial clinical genomic profiling of gliomas-robust and informative with caveats. Exp Mol Pathol 2017; 103:87-93.
Dehghan Harati M, Yu A, Magaki SD, Perez-Rosendahl M, Im K, Park YK, Bergsneider M, Yong WH. Clinicopathologic features and pathogenesis of melanocytic colonization in atypical meningioma. Neuropathology 2018;38:54-61.
Magaki SD, Williams CK, Vinters HV. Glial function (and dysfunction) in the normal & ischemic brain. Neuropharmacology 2018;134:218-225.
Magaki S, Tang Z, Tung S, Williams CK, Lo D, Yong WH, Khanlou N, Vinters HV. The effects of cerebral amyloid angiopathy on integrity of the blood-brain barrier. Neurobiol Aging 2018;70:70-77.
Ferris SP, Velazquez Vega J, Aboian M, Lee JC, Van Ziffle J, Onodera C, Grenert JP, Saunders T, Chen YY, Banerjee A, Kline CN, Gupta N, Raffel C, Samuel D, Ruiz-Diaz I, Magaki S, Wilson D, Neltner J, Al-Hajri Z, Phillips JJ, Pekmezci M, Bollen AW, Tihan T, Schniederjan M, Cha S, Perry A, Solomon DA. High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis. Brain Pathol 2020;30:46-62.
Magaki S, Minasian T, Bork J, Harder SL, Deisch JK. Saksenaea infection masquerading as a brain tumor in an immunocompetent child. Neuropathology 2019;39:382-388.
Oberg KC, Magaki S, Hall J. A standardized autopsy protocol for arthrogryposis (multiple congenital contractures). Am J Med Genet C Semin Med Genet 2019;181:474-478.
Propst R, Denham L, Deisch JK, Kalra T, Zaheer S, Silva K, Magaki S. Sarcina organisms in the upper gastrointestinal tract: a report of three cases with varying presentations. Int J Surg Pathol 2020;28:206-209.
Magaki S, Raghavan R, Minasian T, De Los Reyes K, Kelly T, Farzin-Gohar S, Deisch JK. Papillary craniopharyngioma in a young child: the importance of BRAF mutational testing. Can J Neurol Sci 2019;47:148-150. (letter to the editor)
Mo H, Yau D, Mirshahidi H, Guadiz T, Zuppan CW, Magaki S. AA amyloidosis associated with pulmonary squamous cell carcinoma treated with chemoradiation and immune checkpoint inhibitor therapy. Pathol Int 2020;70:303-305. (letter to the editor)
Book Chapters
Magaki SD, Vinters HV. Tuberous sclerosis. In: Adle-Biassette H, Harding BN, Golden JA, editors. Developmental Neuropathology, 2nd ed. Oxford: International Society of Neuropathology Wiley Blackwell, 2018.
Magaki SD, Tashjian R, Vinters HV. Pediatric vascular malformations. In: Adle-Biassette H, Harding BN, Golden JA, editors. Developmental Neuropathology, 2nd ed. Oxford: International Society of Neuropathology Wiley Blackwell, 2018.
Vinters HV, Magaki SD, Owens GC. Rasmussen encephalitis. In: Adle-Biassette H, Harding BN, Golden JA, editors. Developmental Neuropathology, 2nd ed. Oxford: International Society of Neuropathology Wiley Blackwell, 2018.
Magaki S, Hojat SA, Wei B, So A, Yong WH. An Introduction to the performance of immunohistochemistry. In: Yong WH, editor. Biobanking: Methods & Protocols - A Text in the Methods in Molecular Biology Series, 1st ed. New York: Springer Humana Press, 2019.