From Promise to Practice: Advancing Thoughtful Use of Blood Biomarkers in Alzheimer’s Disease

Dr. Alejandra Sánchez López and Dr. Jason Hinman co-authored “Rational Use of Blood Based Biomarkers for Alzheimer’s Disease: Navigating Between the Hope and the Hype” in the Journal of the American Geriatrics Society, highlighting that while blood based biomarkers can detect Alzheimer’s disease biology, most current tests primarily reflect amyloid pathology rather than cognitive decline. Their clinical value depends on test accuracy, disease prevalence, and patient symptoms, and they should be used only when results are likely to benefit care.

Publication:
Reuben DB, Chambliss AB, Katz BJ, Sánchez López A, Hinman JD. Rational Use of Blood-Based Biomarkers for Alzheimer's Disease: Navigating Between the Hope and the Hype. J Am Geriatr Soc. 2026 Mar 19. doi: 10.1111/jgs.70384. PMID: 41858054 [Online ahead of print.]