David Elashoff, Ph.D.

Division of General Internal Medicine and Health Services Research, Department of Medicine at UCLA

Professor, Biostatistics at UCLA

Core Leader Data Management and Statistical Core

UCLA Med-GIM
1100 Glendon Ave., Suite 1820
Los Angeles, CA 90024
Tel: (310) 794-3346
Email: delashoff@mednet.ucla.edu

Affiliations

ADRC - Data Management and Statistical Core

UCLA Department of Medicine - Statistics Core

UCLA Department of Biostatistics

Research Interests

My primary area of statistical research is in the statistical analysis of high-throughput microarray, proteomic and imaging studies. I also have a strong interest in the methodology for the design and analysis of biomarker discovery and validation studies. I have extensive experience working on cancer related projects with collaborations in oral, lung, prostate, breast and skin cancers. These collaborations include basic science animal studies, biomarker discovery, translational research and clinical trials. My primary appointment is in the Department of Medicine and have a joint appointment in the Department of Biostatistics. I am the director of the Department of Medicine Statistics Core, and a leader of the UCLA CTSI Biostatistics and Computational Biology program.

Education and Degrees

Ph.D. Statistics, Stanford University, Stanford, CA, 2000.

B.S. Mathematics, Massachusetts Institute of Technology, Cambridge, MA, 1995.

Publications

Andrawis JP, Hwang KS, Green AE, Kotlerman J, Elashoff D, Morra JH, Cummings JL, Toga AW, Thompson PM, Apostolova LG. Effects of ApoE4 and maternal history of dementia on hippocampal atrophy. Neurobiol Aging 2012;33(5):856-866. PMCID: PMC3010297

Grill JD, Di L, Lu PH, Lee C, Ringman J, Apostolova LG, Chow N, Kohannim O, Cummings JL, Thompson PM, Elashoff D; Alzheimer's Disease Neuroimaging Initiative. Estimating sample sizes for predementia Alzheimer's trials based on the Alzheimer's Disease Neuroimaging Initiative. Neurobiol Aging 2013 34(1):62-72. PMCID: PMC3412892

Grill JD, Karlawish J, Elashoff D, Vickrey BG. Risk disclosure and preclinical Alzheimer's disease clinical trial enrollment. Alzheimer’s and Dement. 2012 Nov 7. Doi: 10.1016/j.jalz.2012.03.001. PMID: 23141383

Ringman JM, Coppola G, Elashoff D, Rodriguez-Agudelo Y, Medina LD, Gylys K, Cummings JL, Cole GM. Cerebrospinal biomarkers and proximity to diagnosis in preclinical familial Alzheimer’s disease. Dement Geriatr Cogn Disord. 2012;33(1):1-5. doi: 10.1159/000335729. PMID: 22343824

Ringman JM, Elashoff D, Geschwind DH, Welsh BT, Gylys KH, Lee C, Cummings JL, Cole GM. Plasma signaling proteins in persons at genetic risk for Alzheimer's disease: influence of APOE genotype. Arch Neurol 2012;69(6):757-764. doi: 10.1001/archneurol.2012.277. PMID: 22689192

Ringman JM, Fithian AT, Gylys K, Cummings JL, Coppola G, Elashoff D, Pratico D, Moskovitz J, Bitan G. Plasma methionine sulfoxide levels in persons with familial Alzheimer's disease mutations. Dement Geriatr Cogn Disord 2012;33(4):219-225. doi: 10.1159/000338546. PMID: 22584618