Jeffrey Saver, M.D., FAHA, FAAN, FANA

Interim Co-Center Director, Mary S. Easton Center for Alzheimer's Research and Care at UCLA

Distinguished Professor and SA Vice Chair for Clinical Research

Carol and James Collins Chair, Department of Neurology

Director, UCLA Comprehensive Stroke and Vascular Neurology Program

Interim Co-Director, Katherine and Benjamin Kagan Alzheimer's Disease Treatment Development Program

David Geffen School of Medicine at UCLA

UCLA Neurology Clinic
Clinic Appts: (310) 794-1195 {Memory Evaluation}
Clinic Fax: (310) 794-7491

Biography

I am both a behavioral/cognitive and vascular neurologist dedicated to improving brain health through research advances and clinical care. My major research interests are: the neurocognitive consequences of brain vascular disease, acute stroke treatment, stroke prevention, brain imaging, and clinical trial design. In these areas I have authored over 870 research articles, 3 books, and 40 book chapters. I served as principal investigator of the NIH-NINDS FAST-MAG trial, Global Co-PI of the SWIFT PRIME trial, and Chair of the American Heart Association Stroke Council. I am currently Associate Editor at JAMA, the Journal of the American Medical Association and Editorial Board Member at the journal Circulation, and a recipient of the American Heart Association’s Distinguished Scientist Award, the US Clinical Research Foundation’s Clinical Research Award, and the World Stroke Organization Lifetime Research Award.

Specialty

Neurology, stroke and cerebrovascular disease.

Board Certifications

American Board of Psychiatry and Neurology

Medical Board of Illinois and California

Affiliations

Physicians

Alzheimer's Disease Research Center (ADRC)

Katherine and Benjamin Kagan Alzheimer's Disease Treatment Development Program

Education and Degrees

M.D., Harvard Medical School

A.B., magna cum laude, Harvard University

Awards and Honors

William S. Fields Visiting Professor, University of Texas, Houston, 2023

J. Donald Easton Honorary Lecturer, Brown University, 2023

Lifetime Research Award, World Stroke Organization, 2018

Award of Meritorious Achievement, American Heart/Stroke Association, 2017

C Miller Fisher Lecturer and Visiting Professor, Massachusetts General Hospital, Harvard, 2016

Honorary Fellow, European Stroke Organization, 2016

Distinguished Scientist Award, American Heart/Stroke Association, 2015

Distinguished Clinical Research Award for 2014 from the Clinical Research Foundation, 2015

Selected Publications (from over 870)

Saver JL, Klerman EB, Buchan AM, Calleja P, Lizasoain I, Bahr-Hosseini M, Lee S, Liebeskind DS, Mergenthaler P, Mun KT, Ning M, Pelz D, Ray D, Rothwell PM, Seners P, Sreekrishnan A, Sung EM, Tiedt S, Webb AJS, Wölfer TA, Albers GW. Consensus Recommendations for Standardized Data Elements, Scales, and Time Segmentations in Studies of Human Circadian/Diurnal Biology and Stroke. Stroke; 2023 Jul;54(7):1943–1949. PMID: 37272394

Taleb S, Lee JJH, Duncan P, Cramer SC, Bahr-Hosseini M, Su M, Starkman S, Avila G, Hochberg A, Hamilton S, Conwit RA, Saver JL. Essential information for neurorecovery clinical trial design: trajectory of global disability in first 90 days post-stroke in patients discharged to acute rehabilitation facilities. BMC Neurol. England; 2023 Jun 20;23(1):239. PMCID: PMC10280859

Saver JL, Duncan PW, Stein J, Cramer SC, Eng JJ, Lifshitz A, Hochberg A, Bornstein NM. EMAGINE-Study protocol of a randomized controlled trial for determining the efficacy of a frequency tuned electromagnetic field treatment in facilitating recovery within the subacute phase following ischemic stroke. Front Neurol. Switzerland; 2023;14:1148074. PMCID: PMC10196621

Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, Albers GW, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Baxter BW, Devlin TG, Lopes DK, Reddy VK, de Rochemont RD, Singer OC, Jahan R; SWIFT PRIME Investigators. Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke. N Engl J Med 2015; 372:2285-95. PMID: 25882376

Saver JL, Starkman S, Eckstein M, Stratton SJ, Pratt FD, Hamilton S, Conwit R, Liebeskind DS, Sung G, Kramer I, Moreau G, Goldweber R, Sanossian N; FAST-MAG Investigators and Coordinators. Prehospital use of magnesium sulfate as neuroprotection in acute stroke. N Engl J Med 2015;372:528-36. PMCID: PMC4920545

Lee M, Saver JL, Hong KS, Wu YL, Liu HC, Rao NM, Ovbiagele B. Cognitive impairment and risk of future stroke: a systematic review and meta-analysis. CMAJ 2014;186:E536-46. PMCID: PMC4188684

Ringman JM, Sachs MC, Zhou Y, Monsell SE, Saver JL, Vinters HV. Clinical predictors of severe cerebral amyloid angiopathy and influence of APOE genotype in persons with pathologically verified Alzheimer disease. JAMA Neurol 2014 ;71:878-83. PMCID: PMC4101018

Ringman JM, Saver JL, Woolson RF, Clarke WR, Adams HP. Frequency, risk factors, anatomy, and course of unilateral neglect in an acute stroke cohort. Neurology 2004;63:468-474. PMID: 15304577